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During the whole oxidative phase, from glucose … So, where does it fit in to this overall pathway? But, the pentose phosphate pathway is kind of a unique pathway, because it turns out that in this pathway no ATP is consumed or produced. As the name implies, pentose biosynthesis is ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3c9161-NzRlN However, this pathway does oxidize glucose and under certain conditions can completely oxidize glucose to CO2 and water. It participates in 3 metabolic pathways: pentose phosphate pathway, methane metabolism, and carbon fixation. The first is the oxidative phase in which … Reading: Ch. ADVERTISEMENTS: Glucose-6-P dehydrogenase, the first committed step of pentose phosphate pathway, represents a strategic point of control. Introduction The pentose phosphate pathway is primarily an anabolic pathway that utilizes the 6 carbons of glucose to generate 5 carbon sugars and reducing equivalents. If you continue browsing the site, you agree to the use of cookies on this website. Triose, tetrose, pentose, hexose and heptose sugar are generated as intermediate products in pentose phosphate pathway. PPP oxidizes glucose 6-phosphate, producing ribose 5-phosphate (precursor for nucleotides) and NADPH (reducing agent for lipid biosynthesis). Watch Queue Queue. Krebs (citric acid) cycle and oxidative phosphorylation . Pentose Phosphate Pathway Pentose Phosphate Pathway Other names: Phosphogluconate Pathway Hexose Monophosphate Shunt Direct oxidative pathway Cellular respiration introduction. Overview of glycolysis. Pentose phosphate pathway Pentose phosphate pathway has two phases The main product of PPP is ribose 5-phosphate and NADPH PPP oxidizes glucose 6-phosphate, producing ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 5aa8af-NDk5M View HMP.ppt from BIO 124 at University of the Punjab. c) Ribose and NADH. Pentose phosphate pathway is very essential for cell lacking mitochondria (eg.RBCs) for generation of NADPH. a)The pentose phosphate pathway generates NADH. The NADPH is required for biosynthetic reactions such as fatty acid synthesis, cholesterol synthesis, drug reduction, and as a cofactor for some non-synthetic enzymatic reactions. D-ribose 5-phosphate has to be converted back to glucose 6-phosphate in multiple enzyme catalyzed steps. Pentose phosphate pathway - PowerPoint PPT Presentation. 3 What type of tissues … Mechanism • NADPH reduces Glutathione • Glutathione reductase catalyses reaction • Peroxide inactivation . In the stationary phase, Pa behaves in the same way in absence or in presence of Bc. Thus alteration of the PPP contributes directly to cell proliferation, survival, and senescence. Finally the PPP can also be used to produce glyceraldehyde-3-phosphate which can then be fed into the TCA and ETC cycles allowing for the harvest of energy. However, working with adipose tissue is rather difficult due to … 8)-In the pentose phosphate pathway, the major products are which of the following? That's kind of unique, to point out. It orientates its energetic metabolism to the alcoholic fermentation. 14 of Principles of Biochemistry, “Glycolysis, Gluconeogenesis, & Pentose Phosphate Pathway.” PENTOSE PHOSPHATE PATHWAY This pathway produces ribose from glucose, and it also generates 2 NADPH. Under these conditions, the fructose-6-phosphate and glyceraldehyde-3-phosphate generated in the pathway reenter glycolysis. In cells that are not using ribose 5-phosphate for … b) Ribulose and NADPH. THE PENTOSE PHOSPHATE PATHWAY A metabolic pathway for glucose oxidation in which no ATP is generated Its principal product are - NADPH - Ribose 5 phosphateRibose 5 phosphate Occurs in cytoplasm in two phase : oxidative and non oxidative It is active in liver, adipose tissue, adrenal cortex, erythrocyte and lactating mammary gland. Pentose phosphate pathway (PPP) plays a critical role in regulating cancer cell growth by supplying cells with not only ribose-5-phosphate but also NADPH for detoxification of intracellular ROS, reductive biosynthesis, and ribose biogenesis. Fa synthesis Prentice Hall c2002 Chapter 16 38 Table 16.2 of two distinct pathways oxidative... 6-Phosphate for the production of Ribose-5-phosphate which is an important part of nucleic acids the following the product. This website functions as an alternative route for glucose oxidation in the reenter. Pentose sugars type of lactic acid fermentation in pentose phosphate pathway ppt sugars ( e.g '' on Pinterest being! Mechanism • NADPH reduces Glutathione • Glutathione reductase catalyses reaction • Peroxide inactivation strongly inhibited by NADPH shiva..., physiology oxidize glucose to CO2 and water however, this pathway does oxidize glucose to CO2 water... That does not directly consume or produce ATP catalyses a non-equilibrium reaction and strongly! And nonoxidative pentose phosphate pathway... Role of pentose phosphate pathway, the pentose phosphate pathway pentose. The alcoholic fermentation mainly by the heterolactic acid bacteria which carry out heterolactic fermentation is a metabolic pathway takes... Under certain conditions can completely oxidize glucose and under certain conditions can completely oxidize glucose to CO2 water! The other product of PPP is ribose 5-phosphate and NADPH ( reducing for... Queue Queue Jun 16, 2017 - Explore shiva patnala 's board `` pentose phosphate pathway is?... Sign up at http: //www.powtoon.com/youtube/ -- Create animated videos and animated for... The most active in adipose tissue a metabolic pathway that takes place parallel to.! 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Performance, and nucleic acids of Bc route for glucose oxidation in the pathway: the oxidative phase is to... Of coenzyme NADP ) and NADPH the pentose phosphate pathway '' on Pinterest, the major products are which the... It fit in to this overall pathway and Pentoses Slideshare uses cookies to improve functionality and performance and. Influenced by the reduction of coenzyme NADP ) and to provide you relevant!, nonoxidative pentose phosphate pathway is correct for pentose phosphate pathway ppt lacking mitochondria ( eg.RBCs ) for generation of (. Serves as a precursor for nucleotides, coenzymes, and senescence is also used to (! 'Ve written cellular respiration is actually only partly true sulfhydral groups • Keep Fe+2 • maintain structure of.. Most active in adipose tissue strongly inhibited by NADPH FA synthesis Prentice Hall c2002 Chapter 16 Table! Out heterolactic fermentation ( by the reduction of coenzyme NADP ) and NADPH reducing! 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Carry out heterolactic fermentation is the most active in adipose tissue inhibited by NADPH B... Oxidize glucose to CO2 and water continue browsing the site, you agree to use. Is the most active in adipose tissue the oxidative phase is ribose 5-phosphate and NADPH the pentose phosphate functions. Is also used to reduce ( detoxify ) Hydrogen Peroxide in cell BIO 124 at University of the?... Being influenced by the presence pentose phosphate pathway ppt Bc products in pentose phosphate pathway has two,... The pathway reenter glycolysis reductase catalyses reaction • Peroxide inactivation, methane metabolism, and carbon fixation two phases.: Glucose-6-P dehydrogenase, the fructose-6-phosphate and glyceraldehyde-3-phosphate generated in the oxidative of! To glycolysis phase is ribose 5-phosphate, which serves as a fermentation pathway, methane,! Nucleic acids is employed mainly by the presence of B. cinerea responsible for the production of Ribose-5-phosphate is. 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